Stats for mythic rank, last 7 days — third-party aggregation, not an official Moonton figure.
Written by EllieAnth — playing MLBB since 2017 (9+ years), peak rank Mythical Immortal, 1126 stars.
A breakdown of the 8 matchups that decide Natan games — why each one leans the way it does, what it costs you in lane, and how to play it.
Overview
What decides Natan's matchups
Natan dictates lane control by rapidly stacking Theory of Everything through hits with Superposition and Interference!, which grants him vital Attack Speed, Movement Speed, and returning boomerang basic attacks. His greatest power spike comes from Entropy?, where his Reverse-Clone mimics his actions and allows him to swap positions while halving remaining skill cooldowns. However, opponents break Natan's rhythm by dodging his skillshots or catching him before his passive stacks accumulate. Without stacks from Superposition or the escape mobility of Entropy?, Natan's low inherent durability leaves him defenseless when opponents close the gap.
Hard counters 1
These heroes have a structural edge over you: their kit directly shuts down the tools you rely on. Winning the lane outright is rarely the plan — the goal is to limit mistakes, give up as little tempo as possible, and look for value somewhere else on the map.
Zhuxin counters Natan because her continuous displacement through Lantern Flare directly neutralizes his tethered combat style. Natan relies on standing his ground to stack Theory of Everything while coordinating attacks with his Reverse-Clone from Entropy?. Zhuxin easily applies Soul Snare using Fluttering Grace and channeled Lantern Flare, lifting Natan airborne and throwing him away from his clone's range. Even if Natan attempts to disrupt her with Interference!, Zhuxin's shield and mobility during Crimson Beacon allow her to stay in range, forcing Natan to spend his ultimate swap defensively.
Lane impact
Whenever Zhuxin rotates into Natan's lane, his attempt to clear waves using Superposition exposes him to severe punishment. The slow from Fluttering Grace prevents Natan from dodging Lantern Flare, allowing Zhuxin to build maximum Soul Snare stacks effortlessly. Natan cannot rely on Theory of Everything bonus movement speed to escape her persistent field. Consequently, Natan is forced to concede wave priority and farm defensively near his turret, granting Zhuxin free reign to dictate objective tempo, secure the Turtle, or invade the surrounding side lane jungle.
How to play it
As Natan, never cast Entropy? offensively while Zhuxin has Lantern Flare active. Save Superposition strictly for clearing minions from maximum range. When Zhuxin advances using Fluttering Grace, immediately cast Interference! to knock her back before she can apply multiple Soul Snare stacks. If she blinks forward with Crimson Beacon, use the switch active of Entropy? to reposition entirely outside her continuous damage field. Your win condition is to avoid trades, collect safe farm under your turret, and scale into teamfights after Zhuxin's key abilities are baited.
Unfavorable 2
You are behind in this matchup but not helpless. These opponents punish specific mistakes rather than dominating every exchange, so precise cooldown tracking and patient trading keep you in the game.
Lesley holds a structural advantage over Natan due to her superior attack range and instant true damage burst. Her Master of Camouflage grants movement speed while triggering Lethal Shot for unretaliated true damage pokes beyond Natan's basic attack range. Natan relies on landing Superposition and Interference! to build Theory of Everything stacks, but Lesley's stealth state conceals her position and makes skillshot placement difficult. When Natan attempts to close the gap using Entropy?, Lesley immediately denies his engage with Tactical Grenade, resetting her Lethal Shot and forcing Natan to waste his ult duration without ramping up his attack speed.
Lane impact
During the laning phase, Lesley dictates the trade tempo by stepping out of vision with Master of Camouflage and landing a Lethal Shot true damage hit whenever Natan moves up to last hit. Because Natan's returning projectiles from Theory of Everything require precise positioning and hit targets, Lesley can repeatedly poke him down before he can ramp up six stacks. This health deficit forces Natan to play defensively under tower, surrendering gold lane wave priority. Consequently, Lesley gains free rotations toward early Turtle contests while Natan remains trapped clearing waves.
How to play it
To survive this matchup, Natan must avoid trading basic attacks against Lesley's Lethal Shot proc. Instead, clear minion waves safely using Superposition from range, conserving health and stacks. Track Lesley's Tactical Grenade cooldown before committing to an aggressive play; only summon the Reverse-Clone from Entropy? after she wastes her knockback. Position Interference! to disrupt her Master of Camouflage movement path or interrupt Ultimate Snipe if caught in the open. If forced under tower, scale toward mid-game teamfights where Natan's double projectile magic damage outperforms her single-target burst in clustered objectives.
Melissa holds a structural advantage over Natan because Eyes on You! allows her to tether and harass him from beyond his standard attack range without taking retaliation. Furthermore, her passive Doll Buster deals amplified damage to summoned units, meaning Natan's Reverse-Clone created by Entropy? takes increased damage whenever Melissa targets it. To trade back effectively, Natan is forced to spend Interference! defensively to break her momentum or consume his ultimate mobility early, whereas Melissa retains consistent lane dominance with minimal resource investment.
Lane impact
In the Gold Lane, Melissa uses Eyes on You! to pin Natan behind his creep wave, making it dangerous for him to build stacks for Theory of Everything. Should Natan step up to clear minions with Superposition, Melissa can activate Falling! to readjust her distance and extend her tether poke. This consistent range advantage forces Natan to trade HP for minion last-hits, conceding early wave control. Consequently, Natan loses the initiative to assist with the Turtle or secure map vision around the side lane.
How to play it
Natan must respect Melissa's range and track the uptime of Eyes on You!. Once Muddles is deployed away from the wave, immediately stack Theory of Everything on minions using Superposition. If engaging, drop Entropy? to create your Reverse-Clone away from her direct line of fire, minimizing the impact of Doll Buster. Fire Interference! right as she uses Falling! to displace her and interrupt her attack speed window. If she defensively triggers Go Away!, avoid diving the boundary and instead utilize position swaps to hit her with returning basic attacks.
Skill matchups 1
Close matchups decided by execution on both sides. The player who reads cooldowns better, spaces more cleanly and picks the right moment to commit takes the lane — neither kit wins on paper.
Natan's sustain in trades relies on accumulating Theory of Everything stacks and maximizing damage with Entropy?, while Karrie uses Phantom Step to dodge linear skillshots like Superposition. However, Karrie's short base range forces her close, making her vulnerable to Interference!. When Karrie activates Speedy Lightwheel to stack Lightwheel Mark, Natan's knockback interrupts her sequence, forcing her to expend Phantom Step defensively rather than aggressively. Neither hero completely hard counters the other; instead, victory hinges on whether Karrie dodges Natan's crowd control or Natan disrupts Karrie's dual-wield burst window.
Lane impact
In the Gold Lane, Natan holds superior wave clear by lining up Superposition and piercing minion lines with Theory of Everything projectiles. Karrie counters this push by placing Spinning Lightwheel in narrow pathings, applying an 80% slow that denies Natan's preferred positioning. If Natan gets caught by the slow without Entropy? available, Karrie can dash in with Phantom Step and win a chunking trade. Consequently, Natan must manage wave placement carefully, trading heavily only when his passive attack speed stacks are fully capped to maintain tempo for Turtle rotations.
How to play it
Never open a duel with Interference! while Karrie still holds Phantom Step, as she will easily sidestep the attractor and collapse on you. Build six stacks of Theory of Everything on minion waves before stepping into trading range. When Karrie triggers Speedy Lightwheel, deploy Entropy? immediately and use the skill swap to reset distance if she attempts to stack Lightwheel Mark. If caught at low passive stacks, retreat using Superposition for brief zoning and fall back to turret safety until your ultimate cooldown is refreshed.
Favorable 4
Your kit has the edge here. These are the matchups where you should look to build a lead early and convert it, rather than playing for scaling.
Natan holds a structural edge because Interference! directly disrupts Granger's main burst tool during Rhapsody. Granger relies on maintaining a clean line of sight with Rhapsody while adjusting his angle via Rondo, but Natan can knock him back or swap positions entirely using Entropy?. Because Granger's passive Caprice caps his Attack Speed growth, he cannot win prolonged trades against Natan's Theory of Everything, which rapidly builds Attack Speed and Movement Speed stacks whenever Natan lands abilities on Granger or his minion wave.
Lane impact
During the early Gold Lane phase, Granger seeks short trades by dashing in with Rondo and firing Rhapsody. Natan nullifies this wave pressure by casting Superposition through the minion line, keeping pace with wave clear while keeping Interference! ready. If Granger attempts an aggressive trade, getting hit by Interference! ruins his bullet trajectory, forcing him to retreat. Winning these trades gives Natan total control over the minion wave, allowing him to stack Theory of Everything freely and secure priority for early Turtle spawns.
How to play it
Monitor Granger's bullet count under his health bar and avoid trading when Caprice has loaded its guaranteed critical sixth bullet. Always hold Interference! until Granger channels Rhapsody; knocking him sideways cancels his primary damage output and prevents him from reducing Rondo's cooldown. When Granger initiates Death Sonata from range, deploy your Reverse-Clone with Entropy? perpendicular to his sightline and switch places to evade the slow and execute damage. Once his super cannon shots are spent, aggressively close the gap with basic attacks.
Natan holds a structural advantage because the rapid dual-attack output from Entropy? quickly shreds the shield generated by Hanabi's Ninjutsu: Equinox. Stripping this shield removes Hanabi's crowd control immunity, leaving her completely vulnerable to the double knockback from Interference!. While Hanabi relies on Ninjutsu: Petal Barrage to bounce damage off minions, Natan can freely stack Theory of Everything from a safe distance using Superposition. Once fully stacked, his combined Attack Speed and Movement Speed overpower Hanabi's low-mobility kit before her bounce damage can accumulate.
Lane impact
In the Gold Lane, Hanabi attempts to zone Natan by hitting minion waves with Ninjutsu: Soul Scroll to trigger un-decayed Ninjutsu: Petal Barrage bounces. Natan counteracts this by positioning away from his minion wave, forcing Hanabi to choose between wave clear and targeted trades. Using Superposition allows Natan to thin waves cleanly while building Theory of Everything stacks. Securing level four enables Natan to initiate aggressive all-ins with Entropy?, forcing Hanabi out of lane or under her turret, which frees Natan to rotate and contest the Turtle.
How to play it
Monitor Hanabi's shield bar constantly and avoid casting Interference! while Ninjutsu: Equinox is active, as its CC immunity will negate the knockback. Instead, open engagements with Superposition and basic attacks alongside your Reverse-Clone from Entropy? to rapidly break her shield. If Hanabi retaliates with Forbidden Jutsu: Higanbana, immediately activate the second cast of Entropy? to swap locations and avoid the immobilization bloom. With her ultimate negated and her shield destroyed, re-engage with maximum Theory of Everything stacks to execute her.
Layla relies on Malefic Gun to scale her damage at maximum range, but Natan structurally negates this spatial advantage using Entropy?. By placing his Reverse-Clone behind or beside Layla and swapping positions, Natan instantly closes the gap, stripping away the bonus damage she gains from Destruction Rush passive range increases. Once Natan is inside her minimum range, Interference! disrupts her position and interrupts her attacks. Layla is forced to burn Malefic Bomb purely for the decaying movement speed to flee, while Natan stacks Theory of Everything to rapidly overwhelm her low base durability.
Lane impact
During early Gold Lane trades, Layla seeks to hit Malefic Bomb to gain temporary attack range and poke Natan out before he can touch the minion wave. If Natan absorbs this poke without response, Layla pushes the wave under his turret and secures vision. However, whenever Layla misses Malefic Bomb or Void Projectile, a major trade window opens. Natan can quickly clear minions with Superposition, accumulate movement speed from Theory of Everything, and step aggressively into the lane. Winning these trade windows allows Natan to pin Layla under turret, securing early rotation priority toward the Turtle.
How to play it
Track the cast of Malefic Bomb; do not engage while Layla maintains her temporary range and movement speed buff. Instead, wait for her to expend Void Projectile on the minion wave, then cast Entropy? to place a Reverse-Clone near her flank. Instantly swap using Entropy? to double-cast Superposition alongside your clone, locking her down with Interference! if she tries to run. If Layla plays extremely defensively under her turret, stop taking range poke, hold Theory of Everything stacks on side camps, and force objectives with your team.
Natan holds a distinct structural advantage over Miya due to his superior long-range poke and immediate crowd control. Using Superposition, Natan can safely harass Miya while building stacks of Theory of Everything from a distance, forcing her to burn HP before she can stack Moon Blessing via basic attacks. If Miya attempts to aggressively engage with Arrow of Eclipse, Natan can immediately disrupt her pathing using Interference! to knock her back. While Miya's Hidden Moonlight provides a strong cleansing ambush, Natan's Entropy? offers rapid repositioning to negate her burst window.
Lane impact
During the laning phase in Gold Lane, Natan routinely dictates wave control. By hitting Miya or the minion wave with Superposition and Interference!, Natan maintains maximum stacks of Theory of Everything, granting him movement and attack speed advantages that Miya cannot match without full Moon Blessing stacks. Miya is forced to play defensively under her tower, giving up priority. This lane dominance lets Natan rotate early to secure the Turtle or invade the enemy jungle while Miya remains pinned, struggling to clean up waves with Moon Arrow.
How to play it
To maximize this matchup, stack Theory of Everything using Superposition on the minion wave before trading. Save Interference! to disrupt Miya whenever she casts Arrow of Eclipse, stopping her from following up with Moon Arrow. Once Miya unlocks Hidden Moonlight, refrain from committing Entropy? offensively until she reveals her ambush location. If Miya triggers her ultimate to cleanse your CC and gain instant passive stacks, immediately use Entropy? to switch places with your Reverse-Clone, resetting the distance and forcing her to waste her power spike.
Matchup relationships for 1 of these pairings come from the game's own hero data; the rest are selected from the heroes you actually meet in this lane. All written analysis is AI-generated from both heroes' ability kits and reviewed automatically for accuracy — it describes kit interactions, not live win rates.